INSIGHTS

What does it take to build a consulting partnership that truly adapts to the realities of life sciences? In this episode of The Consulting Pulse, Spinnaker co-founder Dane Callow discusses how founder-led consulting, deep domain expertise, and senior-level engagement differentiate Spinnaker in a crowded market—helping life sciences companies navigate evolving operations, finance, and growth challenges.

Amid rapid scientific progress, familiar targets continue to capture momentum while promising alternatives struggle for visibility. A quiet cognitive bias shapes how opportunities are assessed and prioritized. For companies developing novel science, recognizing this pattern—and designing strategies that anticipate and counter it—will be essential to advancing differentiated programs in a landscape defined by precedent.

s Q4 begins, biopharma strategic planning takes center stage. What was once a quarter for cleanup is now a critical reset period for 2026. Investor pressure, pricing reform, transparency mandates, and tariff risks are reshaping commercial priorities. For leadership teams, the challenge is clear: recalibrate forecasts, refine launch plans, and align strategy to today’s realities before competitors pull ahead.

Psychiatry is emerging as the most capital-efficient segment in CNS, attracting major biopharma investment with late-phase assets, validated endpoints, and scalable commercial models. As neurodegeneration remains high-risk, psychiatry offers near-term ROI and strategic fit across the value chain.

A fragmented KOL engagement approach can damage credibility, strain relationships, and lead to missed insights. This article explores the value of a harmonized strategy that aligns Medical Affairs, Clinical Development, and Commercial teams to ensure consistent, strategic interactions. It also highlights the rise of Digital Opinion Leaders and the need to engage emerging voices. A coordinated approach not only builds trust with experts but also drives better outcomes and long

HEOR offers a rigorous, data-driven framework for developing drug pricing strategies that align clinical efficacy and economic value.