INSIGHTS

Explore new targets for CRISPR-based therapeutics, as well as challenges associated with commercialization of these therapies.

A Texas judge's dismissal of WCAS from an FTC antitrust case ensures investor liability standards nationwide.

Navigating the interactions between stakeholders in the healthcare landscape is crucial for the commercial success of any drug launch. This network of relationships and negotiations significantly impacts treatment outcomes, drug pricing, and market access. At the heart of this ecosystem are Pharmacy Benefit Managers (PBMs) whose role is pivotal yet often misunderstood. As intermediaries between health plans, drug manufacturers, and pharmacies, PBMs are tasked with a crucial

In exploring the intricate web of interconnected systems within our bodies, we often overlook the silent powerhouse known as the enteric nervous system (ENS). While the heart and blood vessels take the spotlight in discussions about cardiovascular health, the ENS quietly influences various aspects of our well-being, including the functioning of our cardiovascular system.  The ENS, often dubbed the "second brain," is a sophisticated network of neurons nestled within our...

Clinical trials, a massive hurdle in the biopharmaceutical world, are often the rate-limiting step in drug development. Not only are clinical trial success rates extremely low, but 40% of clinical trials never actually come to fruition due to an inability to meet patient recruitment numbers (1, 2). So how can we create more accurate clinical trials without having to recruit large patient numbers from inaccessible populations? This report explores the potential of real-world

Metabolism is a complex process that facilitates the breakdown of nutrients to generate energy and the production of molecules crucial for cellular function. By supporting energy production, utilization, and storage, metabolism serves as the backbone of physiological health, ensuring the seamless functioning of tissues and organs.    Cancer cells, however, hijack typical metabolic processes, leading to what scientists term "metabolic reprogramming." Fueled by an insatiable ap